The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia

This study investigated the effects of prolonged-release melatonin 2 mg (PRM) on sleep and psychomotor performance in patients aged 55 and above with primary insomnia. The results showed that PRM was significantly better than placebo in improving sleep onset latency, sleep quality, and psychomotor performance, and that there were no rebound effects during withdrawal. Therefore, the study concluded that nightly treatment with PRM is an effective way to induce sleep and improve perceived quality of sleep in older adults with primary insomnia without negatively impacting their daytime psychomotor performance.

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